2010年

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1)     Tomokazu Matsuda, Yoshiaki Kido, Shun-ichiro Asahara, Tsuneyasu Kaisho, Takashi Tanaka, Naoko Hashimoto, Yutaka Shigeyama, Akihiko Takeda, Tae Inoue, Yuki Shibutani, Maki Koyanagi, Tetsuya Hosooka, Michihiro Matsumoto, Hiroshi Inoue, Tohru Uchida, Masato Koike, Yasuo Uchiyama, Shizuo Akira, Masato Kasuga. Ablation of C/EBPβ alleviates ER stress and pancreatic β cell failure through the GRP78 chaperone in mice.  J Clin Invest. 120(1)115-126(2010).


2)     Kazuhito Gotoh, Yoshihiko Tanaka, Akihiko Nishikimi, Risa Nakamura, Hisakata Yamada, Naoyoshi Maeda, Takahiro Ishikawa, Katsuaki Hoshino, Takehito Uruno, Qinhong Cao, Sadayuki Higashi, Yasushi Kawaguchi, Munechika Enjoji, Ryoichi Takayanagi, Tsuneyasu Kaisho, Yasunobu Yoshikai, and Yoshinori Fukui. Selective control of type I IFN induction by the Rac activator DOCK2 during TLR- mediated plasmacytoid dendritic cell activation. J. Exp. Med., 207 (4) 721-730 (2010).

3) Katsuaki Hoshino, Izumi Sasaki, Takahiro Sugiyama, Takahiro Yano, Chihiro Yamazaki, Teruhito Yasui, Hitoshi Kikutani and Tsuneyasu Kaisho. Cutting Edge: Critical Role of IκB Kinase α in TLR7/9-Induced Type I IFN Production by Conventional Dendritic Cells. J Immunol, 184(7)3341-3345(2010)

4) Rie Miyamoto, Tomoki Ito, Shosaku Nomura, Ryuichi Amakawa, Hideki Amuro, Yuichi Katashiba, Makoto Ogata, Naoko Murakami1, Keiko Shimamoto, Chihiro Yamazaki, Katsuaki Hoshino, Tsuneyasu Kaisho and Shirou Fukuhara. Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells. Arthritis Research & Therapy 12:R87 (2010)

5) Hideki Amuro, Tomoki Ito, Rie Miyamoto, Hiroyuki Sugimoto, Yoshitaro Torii, Yonsu Son, Naoto Nakamichi, Chihiro Yamazaki, Katsuaki Hoshino, Tsuneyasu Kaisho, Yoshio Ozaki, Muneo Inaba, Ryuichi　Amakawa, Shirou Fukuhara. 　

Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, function as inhibitors of cellular and molecular components involved in type I interferon production.  Arthritis & Rheumatism 62(7) 2073-2085 (2010).


6)  Chihiro Yamazaki, Rie Miyamoto, Katsuaki Hoshino, Yuri Fukuda, Izumi Sasaki, Masuyoshi Saito, Hironori Ishiguchi, Takahiro Yano, Takahiro Sugiyama, Hiroaki Hemmi, Takashi Tanaka, Eri Hamada, Takeshi Hirashima, Ryuichi Amakawa, Shirou Fukuhara, Shosaku Nomura, Tomoki Ito, Tsuneyasu Kaisho. Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice. Biochem. Biophys. Res. Commun. 397(4) 756-761(2010).

 



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1) 改正恒康. 自然免疫とアレルギー　In 総合アレルギー学　改訂2版、福田健編、南山堂　p63-69（2010）



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1)佐々木泉、 改正恒康. Toll-like receptorによる核酸認識と応答機構. ファルマシア46(1):27-31（2010）.


2)  改正恒康.核酸系免疫アジュバントの特性と作用機構. アレルギー 59 (1): 14-19（2010）.


3)  佐々木泉、 改正恒康.樹状細胞による獲得免疫の制御. 侵襲と免疫19(2):11-16（2010）.


4)  星野克明、 改正恒康. TLRシグナルによるI型インターフェロンの産生. 臨床免疫・アレルギー科学 54 :465-471（2010）.


5) 改正恒康.核酸認識Toll様受容体刺激による樹状細胞からのI型インターフェロン産生誘導機構. 医学のあゆみ 234(5):357-363（2010）.

T. Kaisho. Mechanisms for type I interferon induction from dendritic cells stimulated through nucleic acid recognizing Toll-like receptors. Journal of Clinical and Experimental Medicine (Igaku no Ayumi) 234(5):357-363（2010）.


6) 改正恒康. 核酸に対する樹状細胞応答の制御機構. 炎症と免疫 18(3):234-237（2010）. T. Kaisho. Regulatory mechanisms for dendritic cell responses against nucleic acids. Inflammation & immunity 18(3):234-237（2010）.